The chorus for this song has been playing over and over in my head since I awoke this morning. Goodnight, Irene is a 20th century American folk song first recorded by Huddie "Lead Belly" Ledbetter in 1932 and speaks of a lover's frustration and sadness (and suicidal musings) over a love gone wrong. This song became Lead Belly's theme song and he'd close each performance with it.
Lead Belly website
Wikipedia article on Lead Belly